INFECTION PREVENTION
ally false positives due to blood-culture contamination.
Wolters Kluwer’s POC Advisor
controlled inflammation, organ failure, and death. “If these patients survive, they are often severely debilitated and often wind up back in the ICU or dead in the first year after hospital discharge.”
Chan described how CytoSorb works to combat deadly inflammation in septic pa- tients. “CytoSorb is an extracorporeal cy- tokine adsorber that reduces cytokines and cytokine storm, as well as many bacterial toxins and other mediators that contribute to uncontrolled systemic inflammation. In doing so, CytoSorb has helped to stabilize and turn patients around, reducing organ injury, and restoring adequate blood pres- sure during septic shock.” CytoSorb is compatible with existing dialysis, renal replacement, and extracor- poreal membrane oxygenation machines found in hospital ICUs today. It is ap- proved in the European Union but not yet in the U.S.
“Steripath is a patented closed system that mechanically diverts and seques- ters the initial 1.5 to 2.0 mL of blood, which is known to contain contami- nants, into an isolation chamber. Once diversion is complete, an independent second sterile blood-flow pathway me- chanically opens, allowing only pure, contaminant-free venous blood to flow into the culture bottle.”
“Using standard techniques of the past, hospitals have strived to meet the blood-cul- ture contamination national benchmark of 3 percent. By comparison,” Gerberich said, “Steripath is clinically proven to virtually eliminate blood-culture contamination.” This is important, because an accurate diag- nosis of sepsis helps differentiate between patients who need treatment and those who do not, meaning unnecessary use of antibiotics can be avoided.
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CytoSorb blood purification technology
“By reducing the severity of illness,”
added Chan, “CytoSorb helps to reduce the debilitating effects of sepsis, helps patients get out of the ICU faster, controls costs, and potentially reduces the inci- dence of readmissions later.”
Bob Gerberich, CCO, Magnolia Medical Technologies, talked about the importance of accuracy in blood cultures when diag- nosing sepsis: “Blood-culture contamina- tion introduces substantial uncertainty about accurate diagnosis, as well as a lack of clarity for patients and their families. Forty percent of positive results are actu-
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